Boc-L-His(Boc)-Aib-OH

Product Details

Boc-L-His(Boc)-Aib-OH (protected His-Aib dipeptide) is a protected peptide fragment used in convergent (fragment-condensation) peptide synthesis, which can improve coupling efficiency and reduce racemisation and deletion risk at difficult junctions compared with stepwise assembly. Also known as Boc-His(Boc)-Aib-OH. Side-chain Boc protection is removed together with the resin cleavage, keeping the deprotection scheme simple. Aib (α-aminoisobutyric acid) promotes helical conformation and resists enzymatic cleavage, a feature of several incretin-type peptides. ApiSyn supplies it within a broad protected amino acid range, so peptide programmes can source building blocks from one manufacturer.