Boc-Tyr(tBu)-Aib-OH

Product Details

Boc-Tyr(tBu)-Aib-OH is a protected peptide fragment used in convergent (fragment-condensation) peptide synthesis, which can improve coupling efficiency and reduce racemisation and deletion risk at difficult junctions compared with stepwise assembly. The tert-butyl ester side-chain protection stays intact through chain assembly and is removed in the final TFA cleavage. Aib (α-aminoisobutyric acid) promotes helical conformation and resists enzymatic cleavage, a feature of several incretin-type peptides. ApiSyn can supply it alongside related protected derivatives, which simplifies sourcing for multi-residue sequences.