Cbz-L-Threonine(tBu)-OH (Cbz-Thr(tBu)-OH) is a Cbz
(Z)-protected amino acid for solution-phase peptide synthesis and fragment
condensation, where the Cbz group is removed by hydrogenolysis. Also known as
N-Cbz-O-tert-butyl-L-threonine. The tert-butyl ester side-chain protection
stays intact through chain assembly and is removed in the final TFA cleavage.
ApiSyn supplies it within a broad protected amino acid range, so peptide
programmes can source building blocks from one manufacturer.
| Chemical Name | N-((benzyloxy)carbonyl)-O-(tert-butyl)-L-threonine |
| Molecular Formula | C16H23NO5 |
| Molecular Weight | 309.4 |
| CAS Number | 16966-09-9 |