Fmoc-Ile-Aib-OH (protected Ile-Aib dipeptide) is a protected
peptide fragment used in convergent (fragment-condensation) peptide synthesis,
which can improve coupling efficiency and reduce racemisation and deletion risk
at difficult junctions compared with stepwise assembly. Also known as
Fmoc-isoleucine-alpha-aminoisobutyric acid dipeptide. Aib (α-aminoisobutyric
acid) promotes helical conformation and resists enzymatic cleavage, a feature
of several incretin-type peptides. ApiSyn provides specifications and COA on
request and takes up custom protected amino acids for non-standard sequences.
| Chemical Name | 2-((2S,3S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-methylpentanamido)-2-methylpropanoic acid |
| Molecular Formula | C25H30N2O5 |
| Molecular Weight | 438.5 |
| CAS Number | 2171139-20-9 |