Fmoc-L-Lys[Oct-(OtBu)-Glu-(OtBu)-AEEA-AEEA]-OH (C8-acylated
lysine GLP-1 side chain) is a lipidated linker building block with a
hydrophilic AEEA spacer of the type used to build half-life-extended
(albumin-binding) GLP-1-class peptides. Supplying the side chain as a defined,
pre-assembled intermediate shortens the acylation sequence on the peptide and
moves complex fatty-acid chemistry out of the peptide process. ApiSyn supplies
it for research and process development, with custom synthesis of related linkers
available; end use is subject to applicable patent and licensing review. ApiSyn's
peptide API capability allows building-block supply to be aligned with
downstream peptide scale-up.
| Chemical Name | (23S,50S)-50-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-23-(tert-butoxycarbonyl)-2,2-dimethyl-4,21,26,35,44-pentaoxo-3,30,33,39,42-pentaoxa-22,27,36,45-tetraazahenpentacontan-51-oic acid |
| Molecular Formula | C64H101N5O16 |
| Molecular Weight | 1196.5 |
| CAS Number | 1662688-20-1 |