Fmoc-Pen(Trt)-OH

Product Details

Fmoc-Penicillamine(Trt)-OH (Fmoc-D-Pen(Trt)-OH or L-, confirm stereochemistry) is an Fmoc-protected amino acid building block for Fmoc/tBu solid-phase peptide synthesis (SPPS). Also known as Fmoc-Pen(Trt)-OH. The trityl (Trt) side-chain group is acid-labile, helps keep the residue soluble during coupling and limits side reactions that affect unprotected side chains. The D-configuration is widely used to build protease resistance and stability into peptide drug candidates. ApiSyn supplies it within a broad protected amino acid range, so peptide programmes can source building blocks from one manufacturer.